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5. Infections
Piperacillin / tazobactam
BNF | BNFC | SPC

Hospital-acquired pneumonia, septicaemia, complicated intra-abdominal infections, complicated infections involving the urinary tract or skin and soft tissues; Infections in neutropenic patients

Ticarcillin with clavulanic acid
BNF | BNFC | SPC

Infections due to pseudomonas and proteus spp

Cefalexin
BNF | BNFC | SPC
Ceftriaxone
BNF | BNFC | SPC

North East & Cumbria antimicrobial prescribing guideline for primary care:

"Pelvic Inflammatory Disease: If high risk of gonorrhoea: ADD Ceftriaxone IM 500mg IM stat"

Ceftolozane / tazobactam
BNF | BNFC | SPC

Complicated intra-abdominal infection (licensed), in combination with IV or PO metronidazole, for patients in whom first-line therapy is unsuitable due to limited antibiotic susceptibility.

Complicated urinary tract infection (licensed) where first-line therapy is unsuitable due to limited antibiotic susceptibility.

Acute pyelonephritis (licensed) where first-line therapy is unsuitable due to limited antibiotic susceptibility.

Ertapenem
BNF | BNFC | SPC

Only for one-off use for outpatient antibiotic treatment

Imipenem / Cilastatin
BNF | BNFC | SPC

Primaxim

Aerobic and anaerobic infections; hospital-acquired septicaemia

Meropenem
BNF | BNFC | SPC

Aerobic and anaerobic Gram-positive and Gram-negative infections; hospital-acquired septicaemia

Minocycline (for Acne)
BNF | BNFC | SPC

Tees Do Not Prescribe/Grey List

There are safety concerns associated with minocycline including greater risk of lupus erythematosus-like syndrome and irreversible pigmentation. Minocycline should not routinely be used for the treatment of acne. Oxytetracycline is the current first line treatment choice for acne

North East and Cumbria antimicrobial prescribing guideline for primary care

PrescQIPP Bulletin 60: Minocycline use in acne vulgaris

 

Tigecycline
BNF | BNFC | SPC

For occasional use when all other antimicrobials have proved ineffective. Use must be authorised by an infectious disease consultant

Gentamicin
BNF | BNFC | SPC

Solution for injection

Infections; surgical prophylaxis

Tobramycin
BNF | BNFC | SPC
Daptomycin
BNF | BNFC | SPC

For occasional use when all other antimicrobials have proved ineffective

Dalbavancin
BNF | BNFC | SPC

Microbiologist advice only

Fidaxomicin
BNF | BNFC | SPC
Linezolid
BNF | BNFC | SPC

pneumonia; complicated skin and soft-tissue infections caused by Gram-positive bacteria

Rifaximin
BNF | BNFC | SPC

550mg only

For preventing episodes of overt hepatic encephalopathy, in line with NICE TA337

Teicoplanin
BNF | BNFC | SPC

Clostridium difficile infection; Streptococcal or enterococcal endocarditis; Bone and joint infections

Colistimethate (Cystic Fibrosis)
BNF | BNFC | SPC

Tariff Excluded when delivered by nebulisation/inhalation; NHSE Commissioned

Approved: NICE TA276

Red drug when used for Cystic fibrosis indications only.

 

Colistimethate
BNF | BNFC | SPC

Green HI for Non-Cystic Fibrosis indications only.  CF indications are red

Capreomycin
BNF | BNFC | SPC

Multi-resistant TB

Cycloserine
BNF | BNFC | SPC

Multi-resistant TB

Protionamide
BNF | BNFC | SPC

Multi-resistant TB

Rifampicin
BNF | BNFC | SPC
Methenamine
BNF | BNFC | SPC

Tablets 1g

Treatment of recurrent UTI (3rd line) in line with PHE Antibiotic guidance for primary care

North East & Cumbria antimicrobial prescribing guideline for primary care

Nitrofurantoin
BNF | BNFC | SPC
Efavirenz
BNF | BNFC | SPC

HIV infection

Etravirine
BNF | BNFC | SPC

HIV infection

Nevirapine
BNF | BNFC | SPC

HIV infection

Rilpivirine
BNF | BNFC | SPC

HIV infection

Abacavir
BNF | BNFC | SPC

HIV infection

Didanosine
BNF | BNFC | SPC

HIV infection

Emtricitabine
BNF | BNFC | SPC

HIV Infection

Emtricitabine / rilpivirine / tenofovir
BNF | BNFC | SPC

Eviplera

Odefsey

HIV Infection

Emtricitabine / tenofovir alafenamide (Descovy)
BNF | BNFC | SPC

Descovy

HIV

 

Lamivudine
BNF | BNFC | SPC

HIV infection

Stavudine
BNF | BNFC | SPC

HIV infection

Tenofovir
BNF | BNFC | SPC

Tariff Excluded; NHSE Commissioned

Approved: NICE TA173

Zidovudine
BNF | BNFC | SPC

HIV infection

Abacavir / Lamivudine (Kivexa)
BNF | BNFC | SPC
Enfuvirtide
BNF | BNFC | SPC

HIV Infection

Maraviroc
BNF | BNFC | SPC

HIV Infection

Raltegravir
BNF | BNFC | SPC

HIV infection

Atazanavir
BNF | BNFC | SPC

HIV Infection

Darunavir
BNF | BNFC | SPC

HIV infection

Fosamprenavir
BNF | BNFC | SPC

HIV infection

Indinavir
BNF | BNFC | SPC

HIV infection

Lopinavir / ritonavir
BNF | BNFC | SPC

HIV Infection

Nelfinavir
BNF | BNFC | SPC

HIV infection

Ritonavir
BNF | BNFC | SPC

HIV infection

Saquinavir
BNF | BNFC | SPC

HIV infection

Tipranavir
BNF | BNFC | SPC

HIV infection

Entecavir
BNF | BNFC | SPC

Tariff Excluded; NHSE Commissioned

Approved: NICE TA153

Telbivudine
BNF | BNFC | SPC

Tariff Excluded; NHSE Commissioned

Not Approved: NICE TA154

Boceprevir
BNF | BNFC | SPC

NICE TA253

Daclatasvir
BNF | BNFC | SPC

Tariff Excluded; NHSE Commissioned

Approved: NICE TA364

Elbasvir - Grazoprevir
BNF | BNFC | SPC

Zepatier

Tariff Excluded; NHSE Commissioned

Approved: NICE TA413

Ledipasvir-Sofosbuvir
BNF | BNFC | SPC

Tariff Excluded; NHSE Commissioned

Approved: NICE TA363

Ombitasvir-Paritaprevir-Ritonavir
BNF | BNFC | SPC

Tariff Excluded; NHSE Commissioned

Approved: NICE TA365

Simeprevir
BNF | BNFC | SPC

Not Approved: NICE TA361 (in combination with sofosbuvir)

Sofosbuvir - Velpatasvir
BNF | BNFC | SPC

Tariff-Excluded (NHSE commissioned)

Approved: NICE TA430

Sofosbuvir - Velpatasvir - Voxilaprevir
BNF | BNFC | SPC

Chronic hepatitis C

Tariff-excluded; NHSE commissioned

Approved: NICE TA507

Telaprevir
BNF | BNFC | SPC
Glecaprevir - Pibrentasvir
BNF | BNFC | SPC

Tariff-excluded; NHSE commissioned

Chronic hepatitis C in adults

Approved: NICE TA499

Sofosbuvir
BNF | BNFC | SPC

Tariff Excluded; NHSE Commissioned

Approved: NICE TA330

Palivizumab
BNF | BNFC | SPC

Respiratory syncytial virus

Ribavirin
BNF | BNFC | SPC

Tariff Excluded; NHSE Commissioned

Approved: NICE TA75, TA106, TA200TA300

Paromomycin
BNF | BNFC | SPC

Leishmaniasis

Artesunate
BNF | BNFC | SPC

Treatment of Malaria

Other Antimalarials
BNF | BNFC | SPC

Tees Do Not Prescribe/Grey List

Medication for malaria prophylaxis is not reimbursible by the NHS. 

Prescription only medicines for malaria prophylaxis should be prescribed privately and other medications can be purchased via a local community pharmacy.

Useful prescribing information - a guide for prescribers (51 downloads)

Sodium stibogluconate
BNF | BNFC | SPC

Leishmaniasis

Pentamidine
BNF | BNFC | SPC

Pneumocystis pneumonia

Diethylcarbamazine
BNF | BNFC | SPC

Wuchereria bancrofti infections; brugia malayi infections; loa loa infections

Ivermectin
BNF | BNFC | SPC

Unlicensed Oral formulations

Chronic strongyloides infection; cutaneous larva migrans; scabies

 

Levamisole
BNF | BNFC | SPC

Roundworm infections